Leflunomide Api

Leflunomide Api

22000 INR/Kilograms

Product Details:

  • Molecular Formula C12H9F3N2O2
  • Smell Other
  • Molecular Weight 270.21 Kilograms (kg)
  • HS Code 29420090
  • Shelf Life 3 Years
  • Taste Other
  • Storage Dry Place
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Price And Quantity

  • 100kg Kilograms
  • 22000 INR/Kilograms

Product Specifications

  • C12H9F3N2O2
  • Leflunomide
  • Powder
  • Other
  • 75706-12-6
  • 270.21 Kilograms (kg)
  • Antipyretic Analgesics and NSAIDs
  • Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis
  • 29420090
  • Other
  • 3 Years
  • Medicine Grade
  • 99
  • Dry Place

Trade Information

  • Cash Advance (CA), Cash in Advance (CID), Letter of Credit (L/C), Letter of Credit at Sight (Sight L/C)
  • 2 Week
  • Yes
  • Free samples are available
  • HDPE drums
  • Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Product Description

Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis. Leflunomide therapy is associated with frequent elevations in serum aminotransferase levels and with rare instances of clinically apparent acute liver injury which can be severe and even fatal

Leflunomide is a derivative of isoxazole used for its immunosuppressive and anti-inflammatory properties. As a prodrug, leflunomide is converted to an active metabolite, A77 1726, which blocks dihydroorotate dehydrogenase, a key enzyme of de novo pyrimidine synthesis, thereby preventing the expansion of activated T lymphocytes. This agent also inhibits various protein tyrosine kinases, such as protein kinase C (PKC), thereby inhibiting cell proliferation. (NCI04)

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