Gliclazide APi

8000 INR/Kilograms

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Product Details:

HS Code 29350090
Smell Other
Shelf Life 3 Years
Taste Other
Molecular Formula C15H21N3O3S
Molecular Weight 323.4 Kilograms (kg)
Storage Dry Place
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Price And Quantity

Price 8000 INR/Kilograms
Minimum Order Quantity 100kg Kilograms

Product Specifications

Molecular Weight 323.4 Kilograms (kg)
Molecular Formula C15H21N3O3S
Type Antipyretic Analgesics and NSAIDs
Storage Dry Place
Grade Medicine Grade
Taste Other
Chemical Name Gliclazide
Physical Form Powder
Shelf Life 3 Years
CAS No 21187-98-4
Purity(%) 99
Usage Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).
HS Code 29350090
Smell Other

Trade Information

Payment Terms Cash Against Delivery (CAD), Cash Advance (CA), Cash in Advance (CID), Letter of Credit (L/C), Letter of Credit at Sight (Sight L/C)
Delivery Time 2 Week
Sample Available Yes
Sample Policy Free samples are available
Packaging Details HDPE Drums
Main Export Market(s) Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Product Description

Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It has been classified differently according to its drug properties in which based on its chemical structure, gliclazide is considered a first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release a proton and the presence of one aromatic group. On the other hand, based on the pharmacological efficacy, gliclazide is considered a second-generation sulfonylurea which presents a higher potency and a shorter half-life. Gliclazide belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic cell receptor. Sulfonylureas also increase peripheral glucose utilization, decrease hepatic gluconeogenesis and may increase the number and sensitivity of insulin receptors. Sulfonylureas are associated with weight gain, though less so than insulin. Due to their mechanism of action, sulfonylureas may cause hypoglycemia and require consistent food intake to decrease this risk. The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. Gliclazide has been shown to decrease fasting plasma glucose, postprandial blood glucose and glycosolated hemoglobin (HbA1c) levels (reflective of the last 8-10 weeks of glucose control). Gliclazide is extensively metabolized by the liver; its metabolites are excreted in both urine (60-70%) and feces (10-20%).

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Gliclazide APi

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