Dronedarone HCL

350 USD ($)/Kilograms

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Product Details:

Shelf Life 3 Years
Molecular Formula C31H44N2O5S
Taste Other
Molecular Weight 556.8 Kilograms (kg)
Storage Dry Place
Smell Other
HS Code 29350090
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Price And Quantity

Minimum Order Quantity 100kg Kilograms
Price 350 USD ($)/Kilograms

Product Specifications

Molecular Weight 556.8 Kilograms (kg)
Storage Dry Place
Grade Medicine Grade
Smell Other
HS Code 29350090
Type Antipyretic Analgesics and NSAIDs
Molecular Formula C31H44N2O5S
Taste Other
Physical Form Powder
Usage Dronedarone is a member of the class of 1-benzofurans used for the treatment of cardiac arrhythmias
Purity(%) 99
CAS No 141626-36-0
Shelf Life 3 Years
Chemical Name Dronedarone

Trade Information

Payment Terms Cash Advance (CA), Cash in Advance (CID), Letter of Credit (L/C), Letter of Credit at Sight (Sight L/C)
Delivery Time 2 Week
Sample Available Yes
Sample Policy Free samples are available
Packaging Details HDPE drums
Main Export Market(s) Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Product Description

Dronedarone is a Class III antiarrhythmic drug that works to restore the normal sinus rhythm in patients with paroxysmal or persistent atrial fibrillation. Atrial fibrillation is a common sustained arrhythmia where the treatment primarily focuses on stroke prevention and symptom management. It is managed by rate control, rhythm control, prevention of thromboembolic events, and treatment of the underlying disease. Similar to [amiodarone], dronedarone is a multichannel blocker that works to control rhythm and rate in atrial fibrillation. It meets criteria of all four Vaughan Williams antiarrhythmic drug classes by blocking sodium, potassium, and calcium ion channels and inhibiting -adrenergic receptors. Dronedarone is a related benzofuran compound to amiodarone but its chemical structure lacks iodine moieties which are associated with amiodarone-induced thyroid problems. Additionally, the methyl sulfonyl group in its structure renders dronedarone to be more lipophilic with a shorter half-life than amiodarone. This ultimately leads to reduced tissue accumulation of the drug and decreased risk for organ toxicities, such as thyroid and pulmonary toxicities. Commonly marketed as Multaq dronedarone was approved by the FDA in July 2009 and Health Canada in August 2009. A safety concern for the risk of drug-induced hepatocellular injury has been issued following marketing of dronedarone

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Dronedarone HCL

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